BLOOD-BRAIN-BARRIER FOR EPINEPHRINE IN THE EEL (ANGUILLA-ANGUILLA L)

被引：30

作者：

PEYRAUDWAITZENEGGER, M

SAVINA, A

LAPARRA, J

MORFIN, R

机构：

[1] FAC MED BREST, MED NUCL & BIOPHYS LAB, BREST, FRANCE

[2] INSERM, 453, BORDEAUX, FRANCE

[3] FAC SCI BREST, BIOCHIM LAB, F-29283 BREST, FRANCE

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY | 1979年 / 63卷 / 01期

关键词：

D O I：

10.1016/0306-4492(79)90127-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

By using i.v. injected [14C]labeled epinephrine, it was demonstrated that, in contrast to mammals, catecholamines are able to cross blood-brain barrier in fish. The concentration of [14C]labeled compounds in extracellular fluid was about 25% of that measured in plasma. According to these results, a direct action of plasma catecholamines on fish brain centers for the regulation of physiological functions may be proposed.

引用

页码：35 / 38

页数：4

共 18 条

[1]

AXELROD J, 1959, J PHARMACOL EXP THER, V127, P251

[2] BLOOD-BRAIN BARRIER OF FISH [J].

BERNSTEI.JJ ;

STREICHE.E .

EXPERIMENTAL NEUROLOGY, 1965, 11 (04) :464-&

[3]

BONVALLET M, 1955, J Physiol (Paris), V47, P651

[4]

BRIGHTMAN MW, 1970, 2 P A BENZ S COP, P468

[5] BRAIN-BARRIER SYSTEMS IN SHARKS [J].

CSERR, HF ;

RALL, DP ;

FENSTERMACHER, JD .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, 1972, 42 (1A) :73-+

[6]

FERGUSON RK, 1969, EXP BRAIN RES, V7, P181

[7]

GLOWINSKI J, 1964, J PHARMACOL EXP THER, V146, P48

[8]

HEISEY SR, 1968, COMP BIOCHEM PHYSIOL, V26, P489

[9]

HERMANN H., 1960, JOUR PHYSIOL [PARIS], V52, P118

[10]

HUGGEL HJ, 1969, J PHYSIOL-PARIS, V61, P145

← 1 2 →