NOVEL INSIGHT INTO THE STEREOCHEMICAL PATHWAY LEADING TO (6-4) PYRIMIDINE-PYRIMIDONE PHOTOPRODUCTS IN DNA

被引：27

作者：

CLIVIO, P

FOURREY, JL

GASCHE, J

FAVRE, A

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

[2] CNRS,INST JACQUES MONOD,PHOTOBIOL MOLEC LAB,F-75251 PARIS 05,FRANCE

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 12期

关键词：

PHOTOCHEMISTRY; DNA; 6-4; LESIONS; UV LIGHT; SKIN CANCER;

D O I：

10.1016/S0040-4039(00)91688-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Irradiation of the dinucleoside phosphate 5 led to three photoproducts which were fully characterized, the formation of thietane 9 provides evidence suggesting a novel minor pathway to ''6-4'' lesions in DNA.

引用

页码：1615 / 1618

页数：4

共 12 条

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[7] THE THYMINE-THYMINE PYRIMIDINE-PYRIMIDONE(6-4) ULTRAVIOLET-LIGHT PHOTOPRODUCT IS HIGHLY MUTAGENIC AND SPECIFICALLY INDUCES 3' THYMINE-TO-CYTOSINE TRANSITIONS IN ESCHERICHIA-COLI
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[8] THE BIOLOGY OF THE (6-4) PHOTOPRODUCT
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[9] UV IRRADIATION OF NUCLEIC-ACIDS - FORMATION, PURIFICATION AND SOLUTION CONFORMATIONAL-ANALYSIS OF THE 6-4 LESION OF DTPDT
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[J]. NUCLEIC ACIDS RESEARCH, 1985, 13 (16) : 5949 - 5963
[10] Stromberg R, 1987, Nucleic Acids Symp Ser, P185

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