MAPPING OF THE REGULATORY TYPE I-ALPHA AND CATALYTIC BETA-SUBUNITS OF CAMP-DEPENDENT PROTEIN-KINASE AND INTERLEUKIN-1-ALPHA AND 1-BETA IN THE PIG

被引：12

作者：

MELLINK, C ^{[1
]}

LAHBIBMANSAIS, Y ^{[1
]}

YERLE, M ^{[1
]}

GELLIN, J ^{[1
]}

机构：

[1] INRA,CTR TOULOUSE,GENET CELLULAIRE LAB,F-31326 CASTANET TOLOSAN,FRANCE

来源：

MAMMALIAN GENOME | 1994年 / 5卷 / 05期

关键词：

D O I：

10.1007/BF00389544

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The gene coding for the regulatory type I alpha subunit (PRKAR1A) and the catalytic beta subunit (PRKACB) of cAMP-dependent protein kinase and the genes for interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B) were localized in the pig by means of radioactive in situ hybridization. PRKAR1A was mapped to 12p1.4 and PRKARB to 6q3.1 --> q3.3. The genes for IL1A and IL1B were both assigned to Chromosome (Chr) 3, in the region q1.2 --> q1.3 and q1.1 --> q1.4, respectively. The cDNA nucleotide sequences of these porcine genes were compared with those of human, mouse and cattle. The location of the genes was discussed in relation to the position of their homologous loci in these mammalian species.

引用

页码：298 / 302

页数：5

共 37 条

[1] MULTIPLE MESSENGER-RNA SPECIES CODE FOR THE CATALYTIC SUBUNIT OF THE CAMP-DEPENDENT PROTEIN-KINASE FROM LLC-PK1 CELLS - EVIDENCE FOR 2 FORMS OF THE CATALYTIC SUBUNIT [J].

ADAVANI, SR ;

SCHWARZ, M ;

SHOWERS, MO ;

MAURER, RA ;

HEMMINGS, BA .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1987, 167 (02) :221-226

[2]

ANDERSSON L, 1993, ANIM GENET, V24, P205, DOI 10.1111/j.1365-2052.1993.tb00290.x

[3] THE TISSUE-SPECIFIC EXTINGUISHER LOCUS TSE1 ENCODES A REGULATORY SUBUNIT OF CAMP-DEPENDENT PROTEIN-KINASE [J].

BOSHART, M ;

WEIH, F ;

NICHOLS, M ;

SCHUTZ, G .

CELL, 1991, 66 (05) :849-859

[4] CHROMOSOMAL LOCALIZATION OF MURINE INTERLEUKIN-1 ALPHA-GENES AND BETA-GENES [J].

BOULTWOOD, J ;

BRECKON, G ;

BIRCH, D ;

COX, R .

GENOMICS, 1989, 5 (03) :481-485

[5]

CLARK BD, 1986, NUCLEIC ACIDS RES, V14, P7898

[6] INTERLEUKIN-1 [J].

DINARELLO, CA .

REVIEWS OF INFECTIOUS DISEASES, 1984, 6 (01) :51-95

[7] A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY [J].

FEINBERG, AP ;

VOGELSTEIN, B .

ANALYTICAL BIOCHEMISTRY, 1983, 132 (01) :6-13

[8]

Feltes R., 1993, Animal Genetics, V24, P141, DOI 10.1111/j.1365-2052.1993.tb00262.x

[9]

FORSTER M, 1984, 6TH P EUR C CYT DOM, P351

[10] LOCALIZATION OF THE ALPHA-CASEIN AND BETA-CASEIN GENES TO THE Q24 REGION OF CHROMOSOME-12 IN THE RABBIT (ORYCTOLAGUS-CUNICULUS L) BY INSITU HYBRIDIZATION [J].

GELLIN, J ;

ECHARD, G ;

YERLE, M ;

DALENS, M ;

CHEVALET, C ;

GILLOIS, M .

CYTOGENETICS AND CELL GENETICS, 1985, 39 (03) :220-223

← 1 2 3 4 →