ANALYSIS OF POLAR METABOLITES OF ORGANOPHOSPHORUS INSECTICIDES ON AN ANION-EXCHANGE CHROMATOGRAPHIC COLUMN

被引：6

作者：

HOUX, NWH

JONGEN, WMF

DEVRIES, AW

WELLING, W

DEKKER, A

机构：

[1] Laboratory Fur Research on Insecticides, Wageningen, 6709 PG

[2] Department of Toxicology, Agricultural University, Wageningen

来源：

PESTICIDE SCIENCE | 1979年 / 10卷 / 03期

关键词：

D O I：

10.1002/ps.2780100302

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

A simple and rapid procedure is described for the qualitative and quantitative analysis of metabolites of malathion and other insecticides. The omission of an extraction at low pH, and mild conditions of anion‐exchange chromatography on QAE‐Sephadex prevent the degradation of a malathion metabolite, S‐(1‐carboxy‐2‐ethoxycarbonyl)‐ethyl O,O‐dimethyl phosphorothioate (malaoxon α‐carboxylic acid), which takes place under strongly acid conditions. Disadvantages of the commonly used fractionation of malathion and malaoxon metabolites based on partitioning are discussed. Copyright © 1979 John Wiley & Sons, Ltd

引用

页码：185 / 200

页数：16

共 24 条

[1] SYNTHESIS OF O,O-DIMETHYL S-(1,2-DICARBETHOXY)ETHYL PHOSPHOROTHIOATE (MALOXON) AND RELATED COMPOUNDS FROM TRIALKYL PHOSPHITES AND ORGANIC DISULFIDES [J].