LIPASE-CATALYZED TRANSESTERIFICATION IN THE SYNTHESIS OF A NEW CHIRAL UNLABELED AND C-14-LABELED SEROTONIN UPTAKE INHIBITOR

被引:21
作者
CREGGE, RJ [1 ]
WAGNER, ER [1 ]
FREEDMAN, J [1 ]
MARGOLIN, AL [1 ]
机构
[1] MERRELL DOW RES INST,INDIANAPOLIS CTR,9550 ZIONSVILLE RD,INDIANAPOLIS,IN 46268
关键词
D O I
10.1021/jo00301a004
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of a new chiral unlabeled and carbon-14 labeled serotonin uptake inhibitor via lipase-catalyzed resolution is described. © 1990, American Chemical Society. All rights reserved.
引用
收藏
页码:4237 / 4238
页数:2
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