THEORETICAL ASPECTS OF CHIRAL SEPARATION IN CAPILLARY ELECTROPHORESIS .2. THE ROLE OF ORGANIC-SOLVENT

被引：222

作者：

WREN, SAC

ROWE, RC

机构：

[1] Pharmaceutical Department, ICI Pharmaceuticals, Macclesfield

来源：

JOURNAL OF CHROMATOGRAPHY | 1992年 / 609卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(92)80181-S

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Previous work in chiral capillary electrophoresis has shown that the addition of methanol to the buffer can lead to either an increase or decrease in separation. This behaviour is explained by a mathematical model. The proposed model is supported by new work on the chiral separation of propranolol enantiomers using buffer systems containing methanol or acetonitrile.

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页码：363 / 367

页数：5

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