ISOLATION AND STRUCTURE DETERMINATION OF PENTALENOLACTONES A,B,D, AND F

被引：38

作者：

CANE, DE

SOHNG, JK

WILLIARD, PG

机构：

[1] Department of Chemistry, Brown University, Providence

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 03期

关键词：

D O I：

10.1021/jo00029a012

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four new metabolites related to pentalenolactone have been isolated, pentalenolactone A (17), B (18), D (7), and F (10), and their structures established by a combination of H-1 and C-12 NMR, H-1 NOE, and H-1 COSY spectroscopy, assisted by molecular modeling calculations. The structure and stereochemistry of pentalenolactone D phenacyl ester (21) was established by X-ray crystallography. Each of these metabolites may be important intermediates or shunt metabolites in the biosynthesis of pentalenolactone (16).

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页码：844 / 851

页数：8

相关论文

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