H-1, NA-23, AND C-13 MR SPECTROSCOPY OF CARTILAGE DEGRADATION IN-VITRO

被引：41

作者：

JELICKS, LA ^{[1
]}

PAUL, PK ^{[1
]}

OBYRNE, E ^{[1
]}

GUPTA, RK ^{[1
]}

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT PHYSIOL & BIOPHYS,BRONX,NY 10461

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1993年 / 3卷 / 04期

关键词：

ARTHRITIS; CARTILAGE; JOINTS; DISEASES; MAGNETIC RESONANCE (MR); SPECTROSCOPY; TISSUE CHARACTERIZATION;

D O I：

10.1002/jmri.1880030403

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Viable bovine nasal cartilage was examined with magnetic resonance (MR) spectroscopy. Digestion of the proteoglycan matrix by papain or trypsin was accompanied by substantial changes in carbon-13, sodium-23, and hydrogen-1 MR spectra and relaxation parameters, with C-13 MR spectra showing the most pronounced changes. These results indicate the potential of MR spectroscopy (and imaging) for noninvasive evaluation of cartilage disease and monitoring of patients with degenerative joint diseases.

引用

页码：565 / 568

页数：4

共 23 条

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