SYNTHESIS OF OPTICALLY-ACTIVE 4-ALKOXYCARBONYL-BETA-LACTAMS FROM L-ASPARTIC ACID

被引：21

作者：

GARCIAALVAREZ, M ^{[1
]}

LOPEZCARRASQUERO, F ^{[1
]}

TORT, E ^{[1
]}

RODRIGUEZGALAN, A ^{[1
]}

MUNOZGUERRA, S ^{[1
]}

机构：

[1] UNIV POLITECN CATALUNA,DEPT INGN QUIM,ETS INGN IND,DIAGONAL 647,E-08028 BARCELONA,SPAIN

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 06期

关键词：

D O I：

10.1080/00397919408011295

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclization of L-aspartic acid to (S)-4-benzyloxycarbonyl-2-azetidinone followed by transesterification of this compound in the presence of titanium (IV) tetrabutoxide proved to be an exceedingly efficient method of general application for the preparation of (S)-4-alkoxycarbonyl-beta-lactams.

引用

页码：745 / 753

页数：9

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