HPLC DETERMINATION OF RESIDUAL IVERMECTIN IN CATTLE DUNG FOLLOWING SUBCUTANEOUS INJECTION

被引：25

作者：

BERNAL, JL

DELNOZAL, MJ

SALAS, M

GALANTE, E

LUMARET, JP

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DIV BIOL ANIM & VEGETAL,E-03080 ALACANT,SPAIN

[2] UNIV MONTPELLIER 3,ZOOGEOG LAB,F-34032 MONTPELLIER 1,FRANCE

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1994年 / 17卷 / 11期

关键词：

D O I：

10.1080/10826079408013491

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Residual ivermectin in cattle dung was determined in order to measure its rate of excretion and persistence under field conditions. The drug was extracted into methanol and subsequently determined by reversed-phase high performance Liquid chromatography using a 300 X 3.9 mm Bondclone C-18 column, 47:33:20 acetonitrile/methanol/water as the mobile phase and UV detection at 245 nm. The determination limit for 5 g of sample was 0.020 mg kg(-1). HPLC analyses for aminoacids in the dung were suggestive of changes in their contents with time, which may account for the differential behaviour of insects attracted by the dung.

引用

页码：2429 / 2444

页数：16

共 26 条

[1]

ALVINERIE M, 1987, ANN RECH VET, V18, P269

[2] IVERMECTIN - A POTENT NEW ANTI-PARASITIC AGENT [J].

CAMPBELL, WC ;

FISHER, MH ;

STAPLEY, EO ;

ALBERSSCHONBERG, G ;

JACOB, TA .

SCIENCE, 1983, 221 (4613) :823-828

[3]

Campbell WC, 1989, IVERMECTIN ABAMECTIN

[4]

CHIOU R, 1987, J CHROMATOGR-BIOMED, V60, P196

[5]

CHIU SHL, 1988, J CHROMATOGR-BIOMED, V77, P217

[6]

COOPER JF, 1991, SRTIEMERE90038

[7]

DICKINSON CM, 1990, J CHROMATOGR-BIOMED, V93, P250

[8]

DOHERTY SJ, 1990, J ASSOC OFF ANA CHEM, V73, P931

[9]

Halley B. A., 1989, Ivermectin and abamectin., P162

[10] INJECTABLE ABAMECTIN CAUSES A DELAY IN SCARABAEINE DUNG BEETLE EGG-LAYING IN CATTLE DUNG [J].

HOULDING, B ;

RIDSDILLSMITH, TJ ;

BAILEY, WJ .

AUSTRALIAN VETERINARY JOURNAL, 1991, 68 (05) :185-186

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