8-HYDROXYPENILLIC ACID - NMR CHARACTERISTICS AND FACILE FORMATION FROM 6-AMINOPENICILLANIC ACID

被引：5

作者：

CASY, AF ^{[1
]}

LIPCZYNSKI, A ^{[1
]}

机构：

[1] UNIV BATH,SCH PHARM & PHARMACOL,BATH BA2 7AY,AVON,ENGLAND

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1994年 / 46卷 / 06期

关键词：

D O I：

10.1111/j.2042-7158.1994.tb03848.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

High field NMR (H-1 and C-13) spectral characteristics in D20 of 8-hydroxypenillic acid and 6-aminopenicillanic acid (6-APA)-sodium bicarbonate mixtures are reported. The ready conversion of 6-APA to 8-hydroxypenillic acid is demonstrated.

引用

页码：533 / 534

页数：2

共 8 条

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