A STEREOSELECTIVE FORMAL SYNTHESIS OF (+/-)-(GAMMA)-LYCORANE

被引：43

作者：

ANGLE, SR

BOYCE, JP

机构：

[1] Department of Chemistry, University of California-Riverside, Riverside

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 35期

基金：

美国国家卫生研究院;

关键词：

AMARYLLIDACEAE ALKALOID; PYRROLE HYDROGENATION; ((GAMMA)-LYCORANE;

D O I：

10.1016/0040-4039(95)01245-D

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Compound 11, a common intermediate in several syntheses of (+/-)-gamma-lycorane, was prepared, from commercially available N-triisopropylsilyl pyrrole, in 13 steps and overall 34% yield. The key step of the synthesis involved the diastereoselective hydrogenation of a substituted pyrrole ring.

引用

页码：6185 / 6188

页数：4

共 16 条

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