AMPLIFIED DIHYDROFOLATE-REDUCTASE GENES ARE LOCALIZED TO A HOMOGENEOUSLY STAINING REGION OF A SINGLE CHROMOSOME IN A METHOTREXATE-RESISTANT CHINESE-HAMSTER OVARY CELL LINE

被引：370

作者：

NUNBERG, JH

KAUFMAN, RJ

SCHIMKE, RT

URLAUB, G

CHASIN, LA

机构：

[1] STANFORD UNIV,DEPT BIOL SCI,STANFORD,CA 94305

[2] STANFORD UNIV,DEPT PHARMACOL,STANFORD,CA 94305

[3] COLUMBIA UNIV,DEPT BIOL SCI,NEW YORK,NY 10027

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1978年 / 75卷 / 11期

关键词：

D O I：

10.1073/pnas.75.11.5553

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5553 / 5556

页数：4

共 18 条

[1]

ALT FW, 1978, J BIOL CHEM, V253, P1357

[2]

ALT FW, 1976, J BIOL CHEM, V251, P3063

[3] TANDEM GENETIC DUPLICATIONS IN PHAGE AND BACTERIA [J].

ANDERSON, RP ;

ROTH, JR .

ANNUAL REVIEW OF MICROBIOLOGY, 1977, 31 :473-505

[4] METAPHASE CHROMOSOME ANOMALY - ASSOCIATION WITH DRUG-RESISTANCE AND CELL-SPECIFIC PRODUCTS [J].

BIEDLER, JL ;

SPENGLER, BA .

SCIENCE, 1976, 191 (4223) :185-187

[5]

BIEDLER JL, 1976, J CELL BIOL, V70, pA117

[6] ECDYSONE-STIMULATED RNA-SYNTHESIS IN IMAGINAL DISKS OF DROSOPHILA-MELANOGASTER - ASSAY BY INSITU HYBRIDIZATION [J].

BONNER, JJ ;

PARDUE, ML .

CHROMOSOMA, 1976, 58 (01) :87-99

[7] PHENOTYPIC EXPRESSION IN ESCHERICHIA-COLI OF A DNA-SEQUENCE CODING FOR MOUSE DIHYDROFOLATE-REDUCTASE [J].

CHANG, ACY ;

NUNBERG, JH ;

KAUFMAN, RJ ;

ERLICH, HA ;

SCHIMKE, RT ;

COHEN, SN .

NATURE, 1978, 275 (5681) :617-624

[8] MUTATIONS AFFECTING ADENINE PHOSPHORIBOSYL TRANSFERASE-ACTIVITY IN CHINESE-HAMSTER CELLS [J].

CHASIN, LA .

CELL, 1974, 2 (01) :37-41

[9]

Deaven L L, 1974, Methods Cell Biol, V8, P179, DOI 10.1016/S0091-679X(08)60451-3

[10]

FASMAN GD, 1976, HDB BIOCH MOL BIOL, V2, P302

← 1 2 →