N-[1-(BENZOTRIAZOL-1-YL)ALKYL]AMIDES, VERSATILE AMIDOALKYLATION REAGENTS .4. A NEW SYNTHETIC ROUTE TO 4H-1,3-OXAZINES

被引：11

作者：

KATRITZKY, AR

PERNAK, J

FAN, WQ

机构：

[1] Department of Chemistry, University of Florida, Gainesville, Florida

[2] Department of Chemistry, University of Florida, Gainesville

来源：

JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG | 1992年 / 334卷 / 02期

关键词：

D O I：

10.1002/prac.19923340203

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A variety of 2,4,6-tri- and 2,4,5,6-tetrasubstituted 4H-1,3-oxazines (7 a-i) were synthesized in excellent yields by the reaction of acetylenes (5) in the presence of aluminum chloride with N-[1-(benzotriazol-1-yl) alkyl]amides 4, themselves readily prepared from benzotriazole (1) with amides (2) and aldehydes (3).

引用

页码：114 / 118

页数：5

共 27 条

[1]

AURICCHIO S, 1979, SYNTHESIS-STUTTGART, P116

[2] REACTIVITY OF NUCLEOPHILE AZIDE WITH AROMATIC HETEROCYCLIC CATIONS .6. 2,4,6-TRIARYL 1,3-OXAZINES [J].

CHERTON, JC ;

DESBENE, PL ;

BAZINET, M ;

LANSON, M ;

CONVERT, O ;

BASSELIER, JJ .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1985, 63 (01) :86-94

[3] 1,3-OXAZINE DERIVATIVES [J].

ECKSTEIN, Z ;

URBANSKI, T .

ADVANCES IN HETEROCYCLIC CHEMISTRY, 1963, 2 :311-342

[4]

ECKSTEIN Z, 1978, ADV HETEROCYCL CHEM, V23, P1

[5]

GABRIEL S, 1917, CHEM BER, V50, P819

[6]

Gambaryan N.P., 1969, IAN SSSR KH, P2059

[7]

GIORDANO C, 1975, GAZZ CHIM ITAL, V105, P1265

[8] OXAZINOMYCIN, A NEW CARBON-LINKED NUCLEOSIDE ANTIBIOTIC [J].

HANEISHI, T ;

OKAZAKI, T ;

HATA, T ;

TAMURA, C ;

NOMURA, M ;

NAITO, A ;

SEKI, I ;

ARAI, M .

JOURNAL OF ANTIBIOTICS, 1971, 24 (11) :797-&

[9]

JOCHIMS JC, 1990, SYNTHESIS-STUTTGART, P763

[10] The transfer of a ss-amino acid into a metoxazine derivative. [J].

Karrer, P ;

Miyamichi, E .

HELVETICA CHIMICA ACTA, 1926, 9 :336-339

← 1 2 3 →