POLYAMINE OXIDASE ACTIVITY IN HUMAN-PREGNANCY SERUM

被引：35

作者：

ILLEI, G

MORGAN, DML

机构：

[1] MRC,CTR CLIN RES,DIV PERINATAL MED,HARROW HA1 3UJ,MIDDLESEX,ENGLAND

[2] MRC,CTR CLIN RES,DIV CELL BIOL,HARROW HA1 3UJ,MIDDLESEX,ENGLAND

来源：

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1979年 / 86卷 / 11期

关键词：

D O I：

10.1111/j.1471-0528.1979.tb10715.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The existence of a spermine oxidizing enzyme was established in human pregnancy serum by a radiochemical method, and a cross‐sectional study of its quantitative profile between 10 and 40 weeks gestation was undertaken. Though there was a wide scatter of values, the rise in the average activity was continuous and highly significant. The flavoprotein inhibitor, quinacrin, inhibited the enzyme activity, while the pyridoxal phosphate inhibitor, isoniazid, had no significant inhibitory effect suggesting that the enzyme is of tissue origin. The possible role of polyamines and their oxidation in physiological immunoregulation is discussed. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：878 / 881

页数：4

共 15 条

[1] IDENTIFICATION OF A THYMIC INHIBITOR (CHALONE) OF LYMPHOCYTE-TRANSFORMATION AS A SPERMINE COMPLEX [J].