LIFE AND DEATH DURING LYMPHOCYTE DEVELOPMENT AND FUNCTION - EVIDENCE FOR 2 DISTINCT KILLING MECHANISMS

被引：75

作者：

STRASSER, A

机构：

[1] Institute of Medical Research, PO Royal Melbourne Hospital, 3050 Vic., The Walter and Eliza Hall

来源：

CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 02期

关键词：

D O I：

10.1016/0952-7915(95)80007-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During their development and after their functional activation most lymphocytes die, either because they fail to receive a survival signal or because they are actively killed. Recent experiments on Bcl-2 and Fas/Apo-1 have provided evidence that these two death processes are subject to distinct genetic control.

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页码：228 / 234

页数：7

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