BIOCHEMICAL-PROPERTIES OF ACETYLCHOLINE-RECEPTOR SUBUNITS FROM TORPEDO-CALIFORNICA

被引：224

作者：

LINDSTROM, J

MERLIE, J

YOGEESWARAN, G

机构：

[1] Institute for Biological Studies, San Diego

[2] Department of Biological Sciences, University of Pittsburgh, Pittsburgh

来源：

BIOCHEMISTRY | 1979年 / 18卷 / 21期

关键词：

D O I：

10.1021/bi00588a003

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four polypeptide chains composing acetylcholine receptors from the electric organ of Torpedo californica were purified by preparative electrophoresis in sodium dodecyl sulfate. Their apparent mole ratio α/β/γ/δ is 2:1:1:1. These chains are not readily distinguished by amino acid or car- bohydrate composition but are distinguished by apparent molecular weight and polypeptide maps. By peptide maps, no extensive homology is evident between these chains or between any of these chains and higher molecular weight chains found in receptor-enriched membrane fragments. © 1979, American Chemical Society. All rights reserved.

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页码：4465 / 4470

页数：6

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