GLACIASTEROL-A AND GLACIASTEROL-B, 9,11-SECOSTEROIDS FROM THE MARINE SPONGE APLYSILLA-GLACIALIS

被引：25

作者：

PIKA, J

TISCHLER, M

ANDERSEN, RJ

机构：

[1] UNIV BRITISH COLUMBIA,DEPT CHEM,VANCOUVER V6T 1Z4,BC,CANADA

[2] UNIV BRITISH COLUMBIA,DEPT OCEANOG,VANCOUVER V6T 1Z4,BC,CANADA

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1992年 / 70卷 / 05期

关键词：

D O I：

10.1139/v92-186

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The glaciasterols, a family of cytotoxic 9,11-secosteroids, have been isolated from extracts of the northeastern Pacific sponge Aplysilla glacialis. The structures of glaciasterol A (2) and glaciasterol B (3) were elucidated by a combination of spectroscopic analysis and chemical interconversions on the native steroid 2 and the diacetate 5 of glaciasterol B (3).

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页码：1506 / 1510

页数：5

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