NEW BIOMATERIALS THROUGH SURFACE SEGREGATION PHENOMENON - NEW QUATERNARY AMMONIUM-COMPOUNDS AS ANTIBACTERIAL AGENTS

被引：71

作者：

NOHR, RS

MACDONALD, JG

机构：

[1] Kimberly-Clark Corporation, Roswell, GA 30076

来源：

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 1994年 / 5卷 / 06期

关键词：

ANTIMICROBIAL COMPOUNDS; SURFACE SEGREGATION; POLYDIMETHYLSILOXANE; QUATERNARY AMMONIUM COMPOUNDS; POLYPROPYLENE NONWOVENS;

D O I：

10.1163/156856294X00239

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Five new trisiloxane quaternary ammonium compounds were synthesized from hydrotrisiloxane with allyl glycidyl ether to yield the epoxy function. Various amines were then reacted to yield trisiloxane amines which were further reacted to methyl substitute or oxidize the beta-carbons in order to provide thermal stability. These new compounds were employed as melt additives in a nonwoven polypropylene fiber extrusion process to produce, through surface segregation, a new biomaterial with antibacterial properties.

引用

页码：607 / 619

页数：13

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