ACTIONS OF DOPAMINE AND ITS DERIVATIVES ON TAENIA CAECUM AND TRACHEAL MUSCLE FROM GUINEA PIG AND VAS DEFERENS FROM RAT

被引:14
作者
TAKAGI, K
TAKAYANAGI, I
OHTA, K
机构
[1] Department of Chemical Pharmacology, Faculty of Pharmaceutical Science, University of Tokyo, Tokyo, Bunkyo-ku
[2] Division of Organic Chemistry, Tokyo Women's Medical College, Tokyo, Shinjuku-ku
关键词
D O I
10.1254/jjp.19.604
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Dopamine and its derivatives in Table 1 were tested with the taenia caecum and tracheal muscle from the guinea pig and the vas deferens from the rat. It was concluded from the present results that dopamine and its derivatives act on both the a and Q-adrenergic receptors and the separate dopamine receptors in peripheral tissues. The relaxant response of the intestinal smooth muscle to nicotine in the presence of atropine which was not blocked by the adrenergic blockers may be attributed to the release of dopmaine. © 1969, The Japanese Pharmacological Society. All rights reserved.
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页码:604 / +
页数:1
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