2,3-ANTI SELECTIVE ALDOL REACTION OF PHENYLACETONITRILE

被引:23
作者
CARLIER, PR
LO, KM
机构
[1] Department of Chemistry, Hong Kong University of Science and Technology, Kowloon, Clear Water Bay
关键词
D O I
10.1021/jo00094a011
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Diastereoselective (3.3:1 to >50:1) aldol reaction of nitriles and aldehydes is reported for the first time; concentration studies and the observed 2,3-anti selectivity suggest the intermediacy of a monomeric N-lithiated nitrile anion.
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页码:4053 / 4055
页数:3
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