ULTRA-HIGH-STRENGTH ABSORBABLE SELF-REINFORCED POLYGLYCOLIDE (SR-PGA) COMPOSITE RODS FOR INTERNAL-FIXATION OF BONE-FRACTURES - INVITRO AND INVIVO STUDY

被引：147

作者：

TORMALA, P ^{[1
]}

VASENIUS, J ^{[1
]}

VAINIONPAA, S ^{[1
]}

LAIHO, J ^{[1
]}

POHJONEN, T ^{[1
]}

ROKKANEN, P ^{[1
]}

机构：

[1] HELSINKI UNIV,CENT HOSP,DEPT ORTHOPAED & TRAUMATOL,SF-00260 HELSINKI,FINLAND

来源：

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1991年 / 25卷 / 01期

关键词：

D O I：

10.1002/jbm.820250102

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The ultra-high-strength, self-reinforced (SR) absorbable polymeric composites, consisting of reinforcement elements, like fibers, and of matrix polymer which have the same chemical element composition as reinforcement, were defined. A method to manufacture self-reinforced, absorbable polyglycolide (SR-PGA) rods of polyglycolide sutures (Dexon) by sintering them partially together at elevated temperature and pressure was presented. The rods with nominal diameters of 1.5 mm, 2.0 mm, 3.2 mm, and 4.5 mm showed initial bending modulus and strength values of 8-15 GPa and 220-405 MPa, respectively. Their initial shear strengths were 165-255 MPa. The smallest rods (diam. 1.5 mm) lost their mechanical strength after implantation in the subcutis of rabbits in 4-5 weeks while the thickest rods retained their strength over 8 weeks. The ultra-high-strength SR-PGA rods were concluded to be suitable for fixation of cancellous bone fractures, osteotomies, and epiphyseal plate fractures where the fixation is not exposed to excessive mechanical stresses and where the loads are predominantly of a shear nature.

引用

页码：1 / 22

页数：22

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