A REEXAMINATION OF THE PATHWAY FOR ORNITHINE BIOSYNTHESIS IN A THERMOPHILIC AND 2 MESOPHILIC BACILLUS SPECIES

被引：30

作者：

SAKANYAN, V

KOCHIKYAN, A

METT, I

LEGRAIN, C

CHARLIER, D

PIERARD, A

GLANSDORFF, N

机构：

[1] CTR ENSEIGNEMENT & RECH IND ALIMENTAIRES & CHIM,COOVI,RES INST,1 AVE EMILE GRYSON,B-1070 BRUSSELS,BELGIUM

[2] UNIV LIBRE BRUXELLES,MICROBIOL LAB,B-1050 BRUSSELS,BELGIUM

[3] VRIJE UNIV BRUSSELS,ERFELIJKHEIDSLEER MICROBIOL LAB,B-1050 BRUSSELS,BELGIUM

[4] PHARMAGEN,YEREVAN 375010,ARMENIA,USSR

来源：

JOURNAL OF GENERAL MICROBIOLOGY | 1992年 / 138卷

关键词：

D O I：

10.1099/00221287-138-1-125

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The expression of Bacillus stearothermophilus genes complementing arginine auxotrophs of Escherichia coli was studied. The activity responsible for the formation of ornithine in B. stearothermophilus was identified as a repressible ornithine acetyltransferase (genetic symbol argJ) encoded by the same DNA fragment as the argC, argA and argB genes. Bacillus subtilis and Bacillus licheniformis displayed the same pattern of enzyme activities as B. stearothermophilus. In contrast to previous reports, these organisms consequently use the cyclic pathway of ornithine biosynthesis. B. stearothermophilus also possesses a broad specificity aminoacylase which exhibits low affinity towards N2-acetyl-L-ornithine.

引用

页码：125 / 130

页数：6

共 28 条

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