THROMBELASTOGRAPHIC PATTERNS FOLLOWING ABDOMINAL AORTIC-SURGERY

被引:36
作者
GIBBS, NM [1 ]
CRAWFORD, GPM [1 ]
MICHALOPOULOS, N [1 ]
机构
[1] SIR CHARLES GAIRDNER HOSP,DEPT HAEMATOL,NEDLANDS,WA 6009,AUSTRALIA
关键词
SURGERY; ABDOMINAL AORTIC BYPASS; COMPLICATIONS; HYPERCOAGULABILITY; BLOOD; COAGULATION; THROMBELASTOGRAPHY;
D O I
10.1177/0310057X9402200506
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Postoperative changes in thrombelastographic patterns were studied in thirty patients undergoing elective abdominal aortic bypass surgery. Native whole blood thrombelastography was performed preoperatively and on days 1, 2, and 3 postoperatively. The thrombelastographic changes included a decrease in r on day one (P < 0.0001), with concurrent increases in alpha (P < 0.0001) and MA (P < 0.001). On days 2 and 3 there were further increases in MA (P < 0.0001). These changes indicate enhanced procoagulant activity and progressive increases in maximum clot strength. The results confirm that hypercoagulability occurs in whole blood following abdominal aortic bypass surgery. Further studies are warranted to determine whether modification of postoperative hypercoagulability reduces the incidence of thrombotic complications in this group of patients.
引用
收藏
页码:534 / 538
页数:5
相关论文
共 12 条
  • [1] PERIOPERATIVE MORBIDITY IN PATIENTS RANDOMIZED TO EPIDURAL OR GENERAL-ANESTHESIA FOR LOWER-EXTREMITY VASCULAR-SURGERY
    CHRISTOPHERSON, R
    BEATTIE, C
    FRANK, SM
    NORRIS, EJ
    MEINERT, CL
    GOTTLIEB, SO
    YATES, H
    ROCK, P
    PARKER, SD
    PERLER, BA
    WILLIAMS, GM
    BRESLOW, MJ
    ROSENFELD, BA
    TAYLOR, D
    BRASFIELD, B
    BOURKE, DL
    BEZIRDJIAN, P
    PAUL, S
    VANNATTA, M
    ACHUFF, S
    BUCHMAN, T
    HEITMILLER, E
    NYHAN, D
    SITZMAN, J
    STEPHENSON, RL
    [J]. ANESTHESIOLOGY, 1993, 79 (03) : 422 - 434
  • [2] CONTI CR, 1987, CIRCULATION S5, V75, P85
  • [3] DICKBW, 1988, HEMOSTASIS THROMBOSI, P343
  • [4] Gibbs N M, 1992, J Cardiothorac Vasc Anesth, V6, P680, DOI 10.1016/1053-0770(92)90051-8
  • [5] KEHLET H, 1988, NEURAL BLOCKADE CLIN, P145
  • [6] THROMBELASTOGRAPHY
    MALLETT, SV
    COX, DJA
    [J]. BRITISH JOURNAL OF ANAESTHESIA, 1992, 69 (03) : 307 - 313
  • [7] PERIOPERATIVE CARDIAC MORBIDITY
    MANGANO, DT
    [J]. ANESTHESIOLOGY, 1990, 72 (01) : 153 - 184
  • [8] FACTORS INFLUENCING THROMBUS FORMATION - IN VIVO
    MUSTARD, JF
    DOWNIE, HG
    MURPHY, EA
    ROWSELL, HC
    [J]. AMERICAN JOURNAL OF MEDICINE, 1962, 33 (05) : 621 - +
  • [9] OBRIEN JR, 1984, CLIN LAB HAEMATOL, V6, P239
  • [10] TUMAN KJ, 1987, ANESTH ANALG, V66, P856