TREATMENT BY ASSISTED CONCEPTION OF SEVERE MALE FACTOR INFERTILITY DUE TO SPINAL-CORD INJURY OR OTHER NEUROLOGIC IMPAIRMENT

被引：26

作者：

BRACKETT, NL

ABAE, M

PADRON, OF

LYNNE, CM

机构：

[1] The Miami Project to Cure Paralysis, University of Miami School of Medicine, Miami, 33136, Florida, 1600 N.W. 10th Avenue

[2] Center for Advanced Reproductive Endocrinology, Plantation, Florida

[3] Department of Urology, University of Miami School of Medicine, Miami, Florida

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 1995年 / 12卷 / 03期

关键词：

ELECTROEJACULATION; SPINAL CORD INJURY; IUI; IVF; GIFT;

D O I：

10.1007/BF02211801

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Purpose: This retrospective study evaluated the pregnancy rates of 23 couples with male factor infertility due to traumatic spinal cord injury (N = 21), multiple sclerosis( N = 1) or transverse myelitis (N = 1). Methods: Ovulation induction by clomiphene citrate or gonadotropins was used in combination with intrauterine insemination as an initial approach for assisted conception in all but one couple. Results: Six pregnancies occurred in 60 cycles of intrauterine insemination (mean of 2.6 cycles). In this group, the cumulative pregnancy rate was 26%, Six couples who failed after a total of 33 intrauterine insemination cycles (mean of 5.5 cycles), and 1 couple with no previous intrauterine insemination cycles, initiated 10 cycles of in vitro fertilization (mean of 1.4 cycles). In this group, five pregnancies occurred. The pregnancy rare was 71%. Conclusion: We conclude that ovulation induction in combination with intrauterine insemination offers an effective initial therapy of seve e male factor infertility due to spinal cord injury.

引用

页码：210 / 216

页数：7

共 20 条

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