CONTRACTILE ACTIVITIES OF STRUCTURAL ANALOGS OF LEUKOTRIENES-C AND LEUKOTRIENE-D - ROLE OF THE POLAR SUBSTITUENTS

被引：103

作者：

LEWIS, RA

DRAZEN, JM

AUSTEN, KF

TODA, M

BRION, F

MARFAT, A

COREY, EJ

机构：

[1] HARVARD UNIV,SCH MED,DEPT MED,BOSTON,MA 02115

[2] HARVARD UNIV,SCH PUBL HLTH,SCH MED,DEPT MOLEC PHYS,BOSTON,MA 02115

[3] HARVARD UNIV,DEPT CHEM,CAMBRIDGE,MA 02138

[4] HARVARD UNIV,SCH PUBL HLTH,DEPT MED,BOSTON,MA 02115

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1981年 / 78卷 / 07期

关键词：

D O I：

10.1073/pnas.78.7.4579

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：4579 / 4583

页数：5

共 14 条

[1] Corey E. J., 1980, J AM CHEM SOC, V102, P3663
[2] TOTAL SYNTHESIS OF SLOW REACTING SUBSTANCES (SRS) - LEUKOTRIENE C-2 (11-TRANS-LEUKOTRIENE-C)-(3) AND LEUKOTRIENE-D-(4)
COREY, EJ
CLARK, DA
MARFAT, A
GOTO, G
[J]. TETRAHEDRON LETTERS, 1980, 21 (33) : 3143 - 3146
[3] TOTAL SYNTHESIS OF SLOW REACTING SUBSTANCES (SRSS) - 6-EPI-LEUKOTRIENE-C AND 6-EPI-LEUKOTRIENE-D
COREY, EJ
GOTO, G
[J]. TETRAHEDRON LETTERS, 1980, 21 (36) : 3463 - 3466
[4] STEREOSPECIFIC TOTAL SYNTHESIS OF A SLOW REACTING SUBSTANCE OF ANAPHYLAXIS, LEUKOTRIENE C-1
COREY, EJ
CLARK, DA
GOTO, G
MARFAT, A
MIOSKOWSKI, C
SAMUELSSON, B
HAMMARSTROM, S
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (04) : 1436 - 1439
[5] COMPARATIVE AIRWAY AND VASCULAR ACTIVITIES OF LEUKOTRIENE-C-1 AND LEUKOTRIENE-D INVIVO AND INVITRO
DRAZEN, JM
AUSTEN, KF
LEWIS, RA
CLARK, DA
GOTO, G
MARFAT, A
COREY, EJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07): : 4354 - 4358
[6] COMPARATIVE RESPONSES OF TRACHEAL SPIRALS AND PARENCHYMAL STRIPS TO HISTAMINE AND CARBACHOL INVITRO
DRAZEN, JM
SCHNEIDER, MW
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1978, 61 (06) : 1441 - 1447
[7] CONTRACTILE ACTIVITIES OF STRUCTURAL ANALOGS OF LEUKOTRIENE-C AND LEUROTRIEN-D - NECESSITY OF A HYDROPHOBIC REGION
DRAZEN, JM
LEWIS, RA
AUSTEN, KF
TODA, M
BRION, F
MARFAT, A
COREY, EJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (05): : 3195 - 3198
[8] SLOW REACTING SUBSTANCES OF ANAPHYLAXIS - IDENTIFICATION OF LEUKOTRIENES-C-1 AND LEUKOTRIENES-D FROM HUMAN AND RAT SOURCES
LEWIS, RA
AUSTEN, KF
DRAZEN, JM
CLARK, DA
MARFAT, A
COREY, EJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (06): : 3710 - 3714
[9] IDENTIFICATION OF THE C(6)-S-CONJUGATE OF LEUKOTRIENE-A WITH CYSTEINE AS A NATURALLY-OCCURRING SLOW REACTING SUBSTANCE OF ANAPHYLAXIS (SRS-A) - IMPORTANCE OF THE 11-CIS-GEOMETRY FOR BIOLOGICAL-ACTIVITY
LEWIS, RA
DRAZEN, JM
AUSTEN, KF
CLARK, DA
COREY, EJ
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 96 (01) : 271 - 277
[10] MORRIS HR, 1980, NATURE, V285, P104, DOI 10.1038/285104a0

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