A COMMON AND GENERAL ACCESS TO BERBERINE AND BENZO[C]PHENANTHRIDINE ALKALOIDS

被引:33
作者
BEUGELMANS, R [1 ]
BOISCHOUSSY, M [1 ]
机构
[1] CNRS, INST CHIM SUBSTANCES NAT, F-91198 GIF SUR YVETTE, FRANCE
关键词
SRN1; 3-ARYL ISOQUINOLONES; BERBERINES; BENZOPHENANTHRIDINES;
D O I
10.1016/S0040-4020(01)80496-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The S(RN)1 reactions between o-iodobenzamides and the enolate anion from 2-acetyl homoveratric acid lead to key tricyclic compounds which are easily converted to either berberine or benzo [c] phenanthridine ring systems providing thus a high-yielding and versatile access to both classes of alkaloids.
引用
收藏
页码:8285 / 8294
页数:10
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