MALONATE HALF-ESTERS OF HOMOLANOSTANOID FROM AN ASIAN GANODERMA FUNGUS

被引：21

作者：

CHAIRUL

TOKUYAMA, T

NISHIZAWA, M

SHIRO, M

TOKUDA, H

HAYASHI, Y

机构：

[1] OSAKA CITY UNIV, FAC SCI, OSAKA 558, JAPAN

[2] NATL CTR RES BIOL, BOGOR 16122, INDONESIA

[3] TOKUSHIMA BUNRI UNIV, TOKUSHIMA 770, JAPAN

[4] SHIONOGI & CO LTD, SHIONOGI RES LAB, OSAKA 553, JAPAN

[5] KYOTO UNIV, FAC MED, KYOTO 606, JAPAN

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 03期

基金：

日本学术振兴会;

关键词：

anti-tumour promoter; carboxyacetylquercinic acid derivatives; Ganoderma sp; homolanostanoids; Polyporaceae;

D O I：

10.1016/0031-9422(90)80047-K

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

From the fruit body of an Indonesian Ganoderma species (Polyporaceae), malonic acid half-esters of two new homolanostanoid triterpene hydroxyacids have been isolated along with carboxyacetylquercinic acid, and characterized as their methyl esters. The stereochemistry of carboxyacetylquercinic acid was established by the X-ray crystallography of its methyl ester, and the structures of the two new components were determined by spectral analysis and comparisons with the methyl ester of carboxyacetylquercinic acid. An anti-tumour promoting activity of these quercinic acid derivatives is also reported. © 1990.

引用

页码：923 / 928

页数：6

共 17 条

[1]

ADAM HK, 1967, TETRAHEDRON LETT, P1461

[2] NMR SIGNALS OF METHYL GROUPS OF TRITERPENES WITH OXYGEN FUNCTIONS AT POSITIONS 2 3 AND 23 [J].