INTERACTION OF MERCURIALS WITH HELICAL AND RANDOM POLYURIDYLIC ACID

被引：7

作者：

MILLAR, DB

机构：

[1] Laboratory of Physical Biochemistry, Naval Medical Research Institute, Bethesda

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1968年 / 166卷 / 03期

关键词：

D O I：

10.1016/0005-2787(68)90369-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The interaction of Hg2+ and methyl mercury hydroxide with minimally structured and helical polyuridylic acid (poly U) has been studied. From spectral and hydrodynamic data it is concluded that both the mercurials destroy the helical form of poly U. Both complex types destroy interbase hydrogen bonds but Hg2+ replaced native hydrogen bonds by mercury links forming a product with some degree of order. The monovalent mercurial does not do this. Comparison of the mercurated spectra of poly U at low temperature and DNA suggests that the hydrogen-bonded helix form of poly U is at least double stranded. © 1968.

引用

页码：628 / &

共 13 条

[1] EFFECT OF SOLUTION COMPOSITION UPON POLY U1 [J].