DETECTION OF LOW AVIDITY ANTI-DNA ANTIBODIES IN SYSTEMIC LUPUS-ERYTHEMATOSUS

被引：54

作者：

RILEY, RL

MCGRATH, H

TAYLOR, RP

机构：

[1] UNIV VIRGINIA,SCH MED,DEPT BIOCHEM,CHARLOTTESVILLE,VA 22908

[2] UNIV VIRGINIA,SCH MED,DEPT RHEUMATOL,CHARLOTTESVILLE,VA 22903

来源：

ARTHRITIS AND RHEUMATISM | 1979年 / 22卷 / 03期

关键词：

D O I：

10.1002/art.1780220303

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The binding of sonicated, radiolabeled DNA by systemic lupus erythematosus (SLE) sera was measured by a high sensitivity polyethylene glycol (PEG) precipitation assay. This method is considerably more sensitive than currently used techniques. The results suggest that a significant concentration of low avidity antibodies is present in SLE sera; however, these antibodies are not detected by conventional techniques. Copyright © 1979 American College of Rheumatology

引用

页码：219 / 225

页数：7

共 40 条

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