PULMONARY NOCARDIOSIS CONCURRENT WITH PNEUMOCYSTIS-CARINII PNEUMONIA IN 2 PATIENTS UNDERGOING IMMUNOSUPPRESSIVE THERAPY

被引：9

作者：

PERSCHAK, H ^{[1
]}

GUBLER, J ^{[1
]}

SPEICH, R ^{[1
]}

RUSSI, E ^{[1
]}

机构：

[1] UNIV HOSP ZURICH,DEPT INTERNAL MED,CH-8091 ZURICH,SWITZERLAND

来源：

JOURNAL OF INFECTION | 1991年 / 23卷 / 02期

关键词：

ACQUIRED IMMUNODEFICIENCY SYNDROME; INFECTION; SURVIVAL; LUNG;

D O I：

10.1016/0163-4453(91)92219-U

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Two cases with concomitant pulmonary nocardiosis and Pneumocystis carinii pneumonia are described. The first patient developed pneumonia 3 months after heart transplantation while undergoing standard immunosuppressive therapy with cyclosporin, azathioprine and prednisone. The second patient was treated with chemotherapy and subsequent radiotherapy of the mediastinum for a malignant epithelial tumour. He also received prednisone for paraneoplastic dermatomyositis. Chest Xrays of both patients showed a bilateral interstitial pattern and broncho-alveolar lavage revealed P. carinii. Additional dense and localised pulmonary infiltrates led to suspicion of a further infectious agent, namely, Nocardia asteroides, which was isolated from both patients. Since nocardiosis calls for prolonged treatment, extensive diagnostic measures are needed for its early detection. © 1991 The British Society for the Study of Infection.

引用

页码：183 / &

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