A COMPARATIVE-STUDY ON THE EFFECT OF VARIOUS PHARMACOLOGICAL AGENTS ON THE SURVIVAL OF SKIN FLAPS IN THE RAT

被引:22
作者
NIETO, CS [1 ]
GARCIA, MJS [1 ]
GARCIA, PB [1 ]
机构
[1] UNIV OVIEDO,HOSP COVADONGA,DEPT OTORHINOLARYNGOL,OVIEDO,SPAIN
来源
BRITISH JOURNAL OF PLASTIC SURGERY | 1992年 / 45卷 / 02期
关键词
D O I
10.1016/0007-1226(92)90169-X
中图分类号
R61 [外科手术学];
学科分类号
摘要
The effects of chlorpromazine, pentoxifylline, terbutaline, allopurinol, phenoxybenzamine, naftidrofuryl, hydralazine and trimetazidine were investigated on caudally based dorsal flaps. The study was performed on 108 rats, divided in 9 groups of 12 animals each, one of which served as a control group. All treated groups showed a significantly greater survival of the flap than the control group. Comparisons among different groups showed better outcome in those receiving trimetazidine and hydralazine, followed by those receiving naftidrofuryl and phenoxybenzamine.
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页码:113 / 116
页数:4
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