SIMULTANEOUS EXPRESSION OF T-CELL AND MYELOID CELL PHENOTYPES IN 8 NEWLY ESTABLISHED HTLV-I-POSITIVE T-CELL LINES

被引：7

作者：

KOIZUMI, S ^{[1
]}

SUGIURA, M ^{[1
]}

ZHANG, XK ^{[1
]}

YAMASHIRO, K ^{[1
]}

IWANAGA, M ^{[1
]}

IMAI, S ^{[1
]}

OSATO, T ^{[1
]}

机构：

[1] NATL SAPPORO HOSP,SHIROISHI KU,SAPPORO 060,JAPAN

来源：

JAPANESE JOURNAL OF CANCER RESEARCH | 1992年 / 83卷 / 09期

关键词：

HTLV-I; MYELOID ANTIGEN; CD13; CD33;

D O I：

10.1111/j.1349-7006.1992.tb02002.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Eight cell lines were established from patients with adult T-cell leukemia, and from normal adults, by cocultivation with human T-cell leukemia virus type I(HTLV-I)-producer cell lines in the presence of interleukin-2. All of these cell lines harbored HTLV-I and showed T-cell markers CD2, CD3 and CD4, but not B-cell markers. Unexpectedly, all eight cell lines expressed a myeloid marker CD13 and three of the eight lines also expressed another myeloid marker CD33. Dual staining showed the simultaneous expression of CD3 and CD13 on the same cells. Thus, evidence was obtained for the expression of myeloid antigens on HTLV-I-harboring T cells.

引用

页码：929 / 932

页数：4

共 23 条

[1]

BOWES MA, 1987, IMMUNOLOGY, V60, P247

[2]

CANN AJ, 1990, VIROLOGY, P1501

[3]

FUJII M, 1984, JPN J CANCER RES, V75, P595

[4] A SHORT-LIVED NUCLEAR PHOSPHOPROTEIN ENCODED BY THE HUMAN ETS-2 PROTO-ONCOGENE IS STABILIZED BY ACTIVATION OF PROTEIN KINASE-C [J].

FUJIWARA, S ;

FISHER, RJ ;

BHAT, NK ;

DELAESPINA, SMD ;

PAPAS, TS .

MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (11) :4700-4706

[5]

HATTORI T, 1981, BLOOD, V58, P645

[6] ADULT T-CELL LEUKEMIA - ANTIGEN IN AN ATL CELL-LINE AND DETECTION OF ANTIBODIES TO THE ANTIGEN IN HUMAN-SERA [J].

HINUMA, Y ;

NAGATA, K ;

HANAOKA, M ;

NAKAI, M ;

MATSUMOTO, T ;

KINOSHITA, KI ;

SHIRAKAWA, S ;

MIYOSHI, I .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (10) :6476-6480

[7]

KOBAYASHI T, 1989, LAB INVEST, V60, P370

[8]

KOIZUMI S, 1992, J NATL CANCER I, V84, P690

[9] ISOLATION OF HTLV-TRANSFORMED LYMPHOCYTE-B CLONE FROM A PATIENT WITH HTLV-ASSOCIATED ADULT T-CELL LEUKEMIA [J].

LONGO, DL ;

GELMANN, EP ;

COSSMAN, J ;

YOUNG, RA ;

GALLO, RC ;

OBRIEN, SJ ;

MATIS, LA .

NATURE, 1984, 310 (5977) :505-506

[10] TRANSFER AND EXPRESSION OF THE GENE ENCODING A HUMAN MYELOID MEMBRANE ANTIGEN (GP150) [J].

LOOK, AT ;

PEIPER, SC ;

REBENTISCH, MB ;

ASHMUN, RA ;

ROUSSEL, MF ;

RETTENMIER, CW ;

SHERR, CJ .

JOURNAL OF CLINICAL INVESTIGATION, 1985, 75 (02) :569-579

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