1ST SYNTHESIS OF CARBOCYCLIC OLIGOTHYMIDYLATES

被引：19

作者：

SZEMZO, A

SZECSI, J

SAGI, J

OTVOS, L

机构：

[1] Central Research Institute for Chemistry, Hung. Acad. Sci., H-1525 Budapest

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(00)88833-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5'-O-(dimethoxytrityl)-(+)-carbocyclic thymidine 1 is converted into different 3'-substituted intermediates 2a-c following standard procedures. From these compounds stereochemically pure carbocyclic oligothymidylates 4 are obtained using solid phase synthetic methods. © 1990.

引用

页码：1463 / 1466

页数：4

共 19 条

[1] NUCLEOSIDES AND NUCLEOTIDES .27. SOLID-PHASE SYNTHESIS OF A TRIDECANUCLEOSIDE DODECAPHOSPHATE CONTAINING THE UNNATURAL BASE 4-AMINO-2(1H)-PYRIDINONE AND OF A OCTANUCLEOSIDE HEPTAPHOSPHATE FOR THE DETERMINATION OF THE DNA-POLYMERASE SPECIFICITY [J].