USE OF COLLAGEN SHIELDS IN CATARACT-SURGERY

被引:9
作者
HAASKJOLD, E [1 ]
OHRSTROM, A [1 ]
UUSITALO, RJ [1 ]
KROOTILA, K [1 ]
SANDVIG, KU [1 ]
SONNE, H [1 ]
MAHLBERG, K [1 ]
机构
[1] UNIV HELSINKI,CENT HOSP,DEPT OPHTHALMOL,HAARTMANINKATU 4C,SF-00290 HELSINKI 29,FINLAND
关键词
CATARACT SURGERY; COLLAGEN SHIELD; PERIBULBAR RETROBULBAR INJECTION; POSTOPERATIVE PAIN;
D O I
10.1016/S0886-3350(13)80155-1
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
A randomized, prospective, multicenter study evaluated the efficacy and safety of using collagen shields to deliver drugs after cataract surgery. Collagen shields saturated with an antibiotic and a steroid were placed in 90 eyes postoperatively. A control group of 93 eyes received the same drugs through a peribulbar/retrobulbar injection. One day after surgery, the shield group had significantly less corneal edema, conjunctival hemorrhaging, and postoperative pain and fewer corneal opacities. All symptoms except the conjunctival hemorrhaging disappeared by day seven. Our study suggests that using collagen shields for drug delivery after cataract surgery decreases tissue damage and increases patient comfort without adverse side effects.
引用
收藏
页码:150 / 153
页数:4
相关论文
共 18 条
[1]  
Hardy RG, Paterson CA, Ocular penetration of <sup>14</sup>C-labeled chloramphenicol following subconjunctival or sub-Tenon's injections, Am J Ophthalmol, 71, pp. 1307-1312, (1971)
[2]  
Barza M, Kane A, Baum J, Oxacillin for bacterial endophthalmitis: subconjunctival, intravenous, both, or neither?, Invest Ophthalmol, 19, pp. 1348-1354, (1980)
[3]  
Kishida K, Otori T, A quantitative study on the relationship between transcorneal penetration of drugs and their hydrophobicity, Jpn J Ophthalmol, 24, pp. 251-259, (1980)
[4]  
Kupferman A, Ryan WJ, Leibowitz HM, Prolongation of anti-inflammatory effect of prednisolone acetate, Arch Ophthalmol, 99, pp. 2028-2029, (1981)
[5]  
Wine NA, Gornall AG, Basu PK, The ocular uptake of subconjunctivally injected C14 hydrocortisone, Am J Ophthalmol, 58, pp. 362-366, (1964)
[6]  
Aquavella JV, Ruflini JJ, LoCascio JA, Use of collagen shields as a surgical adjunct, Journal of Cataract & Refractive Surgery, 14, pp. 492-495, (1988)
[7]  
Poland DE, Kaufman HE, Clinical uses of collagen shields, J Cataract Refract Surg, 14, pp. 489-491, (1988)
[8]  
Friedberg ML, Player U, Mondino BJ, Device drug delivery to the eye: collagen shields, iontophoresis, and pumps, Ophthalmology, 98, pp. 725-732, (1991)
[9]  
Unterman SR, Rootman DS, Hill JM, Et al., Collagen shield drug delivery: therapeutic concentrations of tobramycin in the rabbit cornea and aqueous humor, J Cataract Refract Surg, 14, pp. 500-504, (1988)
[10]  
Sawusch MR, O'Brien TP, Dick JD, Gottsch JD, Use of collagen corneal shields in the treatment of bacterial keratitis, American Journal of Ophthalmology, 106, pp. 279-281, (1988)