HEPARIN AFTER ANGIOPLASTY - AN UNRESOLVED ISSUE

被引：8

作者：

MORE, RS ^{[1
]}

BRACK, MJ ^{[1
]}

GERSHLICK, AH ^{[1
]}

机构：

[1] GLENFIELD GEN HOSP,ACAD DEPT CARDIOL,GROBY RD,LEICESTER LE3 9QP,ENGLAND

来源：

EUROPEAN HEART JOURNAL | 1993年 / 14卷 / 11期

关键词：

ANGIOPLASTY RESTENOSIS; HEPARIN;

D O I：

10.1093/eurheartj/14.11.1543

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Restenosis following coronary angioplasty remains a signficant problem. Experinental work suggests that appropriate use of heparin may be beneficial through inhibition of smooth muscle cell proliferation. Possible mechanisms of this effect in various models, are discussed. Limited clinical studies to date, however, have failed to show therapeutic efficacy. Possible reasons for this lack of effect are discussed and the importance of assessing heparin in appropriate clinical trials is emphasized. © 1993 The European Society of Cardiology.

引用

页码：1543 / 1547

页数：5

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