SEROTONIN RECEPTORS ON ASTROCYTES IN PRIMARY CULTURES - EFFECTS OF METHYSERGIDE AND FLUOXETINE

被引：63

作者：

HERTZ, L ^{[1
]}

BALDWIN, F ^{[1
]}

SCHOUSBOE, A ^{[1
]}

机构：

[1] UNIV COPENHAGEN,PANUM INST,DEPT BIOCHEM A,DK-2200 COPENHAGEN N,DENMARK

来源：

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 1979年 / 57卷 / 02期

关键词：

D O I：

10.1139/y79-034

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A specific binding of serotonin (at least 50 fmol/mg protein) was demonstrated in mouse astrocytes in primary cultures. This binding was inhibited by methysergide and by fluoxetine.

引用

页码：223 / 226

页数：4

共 26 条

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[3] DETERMINATION OF BRAIN-SPECIFIC ANTIGENS IN SHORT-TERM CULTIVATED RAT ASTROGLIAL CELLS AND IN RAT SYNAPTOSOMES
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[6] 5-HYDROXYTRYPTAMINE BINDING TO SYNAPTIC-MEMBRANES FROM RAT-BRAIN
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[7] FILLION GMB, 1978, MOL PHARMACOL, V14, P50
[8] GLIAL CELL FUNCTION - UPTAKE OF TRANSMITTER SUBSTANCES
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1971, 68 (11) : 2686 - +
[9] POSSIBLE RELATIONSHIP BETWEEN GLIAL CELLS, DOPAMINE AND EFFECTS OF ANTIPSYCHOTIC-DRUGS
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[J]. NATURE, 1977, 266 (5603) : 637 - 638
[10] HERTZ L, 1978, IN VITRO CELL DEV B, V14, P376

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