PRODUCTION OF APX TOXINS BY FIELD STRAINS OF ACTINOBACILLUS-PLEUROPNEUMONIAE AND ACTINOBACILLUS-SUIS

被引：51

作者：

KAMP, EM ^{[1
]}

VERMEULEN, TMM ^{[1
]}

SMITS, MA ^{[1
]}

HAAGSMA, J ^{[1
]}

机构：

[1] CENT VET INST,DEPT MOLEC BIOL,8200 AB LELYSTAD,NETHERLANDS

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 09期

关键词：

D O I：

10.1128/IAI.62.9.4063-4065.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The three Apr toxins of Actinobacillus pleuropneumoniae have potential value for use in vaccines and diagnostic tests which will be species specific instead of serotype specific, provided that the Apr toxins are species specific and all field strains produce these toxins. We examined 114 A. pleuropneumoniae field strains and found that they secreted either ApxI, ApxII, ApxI and ApxII, or ApxII and ApxIII and secreted no other cytolytic activities. However, proteins similar to ApxI and ApxII were also produced by Actinobacillus suis.

引用

页码：4063 / 4065

页数：3

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