DISSEMINATED CAT-SCRATCH DISEASE - DETECTION OF ROCHALIMAEA-HENSELAE IN AFFECTED TISSUE

被引：57

作者：

WALDVOGEL, K

REGNERY, RL

ANDERSON, BE

CADUFF, R

CADUFF, J

NADAL, D

机构：

[1] UNIV CHILDRENS HOSP,DIV IMMUNOL HAEMATOL,CH-8032 ZURICH,SWITZERLAND

[2] UNIV HOSP ZURICH,DEPT CLIN PATHOL,ZURICH,SWITZERLAND

[3] UNIV HOSP ZURICH,DIV PAEDIAT RADIOL,ZURICH,SWITZERLAND

[4] CTR DIS CONTROL,NATL CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1994年 / 153卷 / 01期

关键词：

CAT-SCRATCH DISEASE; ROCHALIMAEA HENSELAE; ROCHALIMAEA QUINTANA; SEROLOGY; DIAGNOSIS;

D O I：

10.1007/BF02000782

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

An immunocompetent 9-year-old boy with disseminated catscratch disease involving spleen, cervical and abdominal lymph nodes, skull, and one clavicle is reported. Antibodies to Rochalimaea quintana and R. henselae were detected, at increasing, then decreasing concentration. DNA extracted from the biopsied skull lesion was amplified by polymerase chain reaction and hybridized with species-specific oligonucleotides proving the presence of R. henselae in affected tissue. Our findings suggest that R. henselea plays a pathogenic role in cat-scratch disease.

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页码：23 / 27

页数：5

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