SEASONAL FLUCTUATION IN THE INCIDENCE OF INTRACRANIAL ANEURYSM RUPTURE AND ITS RELATIONSHIP TO CHANGING CLIMATIC CONDITIONS

被引:72
作者
CHYATTE, D
CHEN, TL
BRONSTEIN, K
BRASS, LM
机构
[1] VET AFFAIRS MED CTR, NEUROL SERV, W HAVEN, CT USA
[2] DIABLO NEUROSURG MED GRP, WALNUT CREEK, CA USA
关键词
SUBARACHNOID HEMORRHAGE; INTRACRANIAL ANEURYSM; CLIMATE SEASONAL VARIATION; GENDER;
D O I
10.3171/jns.1994.81.4.0525
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Seasonal and climatic variations have been linked to the occurrence of some types of cerebrovascular disease; however, the conditions that lead to intracranial aneurysm rupture are not known. The purpose of the present study was to determine whether seasonal and climatic conditions are related to intracranial aneurysm rupture. Data provided by the Connecticut Health Information Management and Exchange were analyzed for all patients with a primary diagnosis of aneurysmal subarachnoid hemorrhage (SAH) for the fiscal years 1981, 1983, 1985, 1987, 1988, and 1989. Patient records were correlated with climatic conditions for the years 1981 to 1989 obtained from the National Climatic Data Center, National Oceanic and Atmospheric Administration, National Environmental Satellite Data, and Information Service. During the time periods studied, 1487 patients with a primary diagnosis of aneurysmal SAH were treated by reporting hospitals. Seasonal variation in the incidence of aneurysmal SAH and admission clustering were observed but differed significantly between men and women. Men showed a single large peak in late fall(Roger's r = 11.5, p < 0.005), whereas women had an annual peak occurring in late spring (Roger's r = 10.3, p < 0.01). Substantial climatic change occurred during the 72 hours prior to 10 of the 14 clusters of men who were admitted (p < 0.01, Yates' corrected chi-square 7.33, df = 1). In contrast, clusters of women admitted were not related to preceding climatic change (p > 0.25, Yates' corrected chi-square 0.06, df = 1). Hospital admissions for aneurysmal SAH display seasonal fluctuation, with women showing a different seasonal pattern from men. Changing climatic conditions precede aneurysm rupture in men but not in women, which suggests that weather is causally related to aneurysm rupture in men, and that factors that lead to aneurysm rupture in women may be different from those in men. These data do not explain why weather fronts or gradients are associated with aneurysm rupture in men.
引用
收藏
页码:525 / 530
页数:6
相关论文
共 70 条
[1]   CLIMATIC EFFECTS ON BLOOD-PRESSURE IN NORMOTENSIVE AND HYPERTENSIVE SUBJECTS [J].
ABDULLA, K ;
TAKA, M .
POSTGRADUATE MEDICAL JOURNAL, 1988, 64 (747) :23-26
[2]  
Adams C E, 1985, Nurse Pract, V10, P39
[3]   Cerebrovascular Disease: Frequency and Population Selectivity in an Upper Midwestern Community [J].
Alter, Milton ;
Christoferson, Lee ;
Resch, Joseph ;
Myers, Gary ;
Ford, Janet .
STROKE, 1970, 1 (06) :454-465
[4]  
BELEKE H, 1962, Z ANGEW BADER KLIMAH, V9, P530
[5]   CLUSTERING OF STROKES IN ASSOCIATION WITH METEOROLOGIC FACTORS IN THE NEGEV DESERT OF ISRAEL - 1981-1983 [J].
BERGINER, VM ;
GOLDSMITH, J ;
BATZ, U ;
VARDI, H ;
SHAPIRO, Y .
STROKE, 1989, 20 (01) :65-69
[6]   SEASONAL-VARIATION OF STROKE - DOES IT EXIST [J].
BILLER, J ;
JONES, MP ;
BRUNO, A ;
ADAMS, HP ;
BANWART, K .
NEUROEPIDEMIOLOGY, 1988, 7 (02) :89-98
[7]   STROKES AND WEATHER - A QUANTITATIVE STATISTICAL STUDY [J].
BOKONJIC, R ;
ZEC, N .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 1968, 6 (03) :483-&
[8]   SEASONAL-VARIATION IN ARTERIAL BLOOD-PRESSURE [J].
BRENNAN, PJ ;
GREENBERG, G ;
MIALL, WE ;
THOMPSON, SG .
BMJ-BRITISH MEDICAL JOURNAL, 1982, 285 (6346) :919-923
[9]  
BREZITSKAYA ON, 1991, VESTN AKAD MED NAUK+, P42
[10]   THE CONTRIBUTION OF ENVIRONMENTAL-TEMPERATURE AND HUMIDITY TO GEOGRAPHIC VARIATIONS IN BLOOD-PRESSURE [J].
BRUCE, N ;
ELFORD, J ;
WANNAMETHEE, G ;
SHAPER, AG .
JOURNAL OF HYPERTENSION, 1991, 9 (09) :851-858