ROLE OF ELEMENTARY SULPHUR AND ERYTHROCYTE GLUTATHIONE IN FORMATION OF SULPHAEMOGLOBIN

被引：4

作者：

FRENDO, J

机构：

[1] Department of Physiological Chemistry, Medical School, Cracow

来源：

CLINICA CHIMICA ACTA | 1969年 / 24卷 / 01期

关键词：

D O I：

10.1016/0009-8981(69)90133-8

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The formation of sulphaemoglobin was observed during incubation of an elementary sulphur suspension with whole blood haemolysate containing reduced glutathione. It was demonstrated that sulphaemoglobin is formed in the reaction of oxyhaemoglobin with hydrogen sulphide produced from the elementary sulphur due to the reduction by GSH. Blocking the BSH group of glutathione with N-ethylmaleimide or removal of GSH by dialysis prevented the formation of sulphaemoglobin in the presence of elementary sulphur. © 1968.

引用

页码：1 / &

共 13 条

[1] SULFHEMOGLOBINEMIA - A STUDY OF 62 CLINICAL CASES [J].

BRANDENBURG, RO ;

SMITH, HL .

AMERICAN HEART JOURNAL, 1951, 42 (04) :582-588

[2]

Drabkin DL, 1935, J BIOL CHEM, V112, P51

[3]

GREENGARD H, 1940, J BIOL CHEM, V123, P83

[4]

GUTHRIE JOHN D., 1938, CONTR BOYCE THOMPSON INST, V9, P223

[5] Sulphemoglobinemia [J].

Harrop, GA ;

Waterfield, RL .

JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1930, 95 :647-650

[6] EFFECT OF THIOL COMPOUNDS ON SULPHAEMOGLOBIN FORMATION [J].

KOJ, A ;

FRENDO, J .

CLINICA CHIMICA ACTA, 1964, 9 (05) :500-&

[7]

LEMBERG R, 1949, HEMATIN COMPOUNDS BI, P498

[8]

MCCUTHEON AD, 1960, LANCET, P7240

[9] CONGENITAL SULFHEMOGLOBINEMIA [J].

MILLER, AA .

JOURNAL OF PEDIATRICS, 1957, 51 (03) :233-237

[10] SULFHEMOGLOBINEMIA FOLLOWING HABITUAL USE OF ACETANILID [J].

REYNOLDS, TB ;

WARE, AG .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1952, 149 (17) :1538-1541

← 1 2 →