CHRONIC ZINC-DEFICIENCY ALTERS NEURONAL FUNCTION OF HIPPOCAMPAL MOSSY FIBERS

被引：133

作者：

HESSE, GW

机构：

[1] Department of Psychology, Harvard University, Cambridge

来源：

SCIENCE | 1979年 / 205卷 / 4410期

关键词：

D O I：

10.1126/science.224456

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Low-frequency stimulation of hippocampal mossy fiber axons in zincdeficient adult rats produced synoptic responses that declined in amplitude with successive stimuli. This response decrement is abnormal and suggests that the heavy deposits of zinc in mossy fiber boutons are important for synoptic transmission.

引用

页码：1005 / 1007

页数：3

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