INVITRO METABOLISM OF MISONIDAZOLE

被引：30

作者：

JOSEPHY, PD

PALCIC, B

SKARSGARD, LD

机构：

[1] UNIV BRITISH COLUMBIA,VANCOUVER V6T 1W5,BC,CANADA

[2] BRITISH COLUMBIA CANC RES CTR,MED BIOPHYS UNIT,VANCOUVER,BC,CANADA

来源：

BRITISH JOURNAL OF CANCER | 1981年 / 43卷 / 04期

关键词：

D O I：

10.1038/bjc.1981.65

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：443 / 450

页数：8

共 22 条

[1]

DISCHE S, 1978, INT J RAD ONCOLOGY B, V5, P775

[2] PHARMACOKINETIC AND METABOLIC STUDIES OF HYPOXIC CELL RADIOSENSITIZER MISONIDAZOLE [J].

FLOCKHART, IR ;

LARGE, P ;

TROUP, D ;

MALCOLM, SL ;

MARTEN, TR .

XENOBIOTICA, 1978, 8 (02) :97-105

[3] HYPOXIC SENSITIZERS - RADIOBIOLOGICAL STUDIES AT CELLULAR LEVEL [J].

HALL, EJ ;

ROIZINTOWLE, L .

RADIOLOGY, 1975, 117 (02) :453-457

[4] ASCORBATE-ENHANCED CYTOTOXICITY OF MISONIDAZOLE [J].

JOSEPHY, PD ;

PALCIC, B ;

SKARSGARD, LD .

NATURE, 1978, 271 (5643) :370-372

[5]

JOSEPHY PD, BIOCH PHARMACOL

[6]

JOSEPHY PD, 1980, RAD SENSITIZERS, P61

[7] MECHANISM OF MICROSOMAL AND MITOCHONDRIAL NITROREDUCTASE - ELECTRON-SPIN RESONANCE EVIDENCE FOR NITROAROMATIC FREE-RADICAL INTERMEDIATES [J].

MASON, RP ;

HOLTZMAN, JL .

BIOCHEMISTRY, 1975, 14 (08) :1626-1632

[8] RADIOSENSITIZING AND TOXIC EFFECTS OF 2-NITROIMIDAZOLE RO-07-0582 IN HYPOXIC MAMMALIAN-CELLS [J].

MOORE, BA ;

PALCIC, B ;

SKARSGARD, LD .

RADIATION RESEARCH, 1976, 67 (03) :459-473

[9] ELECTRON-SPIN RESONANCE SPIN TRAPPING - DETECTION OF SUPEROXIDE FORMATION DURING AEROBIC MICROSOMAL REDUCTION OF NITRO-COMPOUNDS [J].

SEALY, RC ;

SWARTZ, HM ;

OLIVE, PL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 82 (02) :680-684

[10] SULFHYDRYLS, ASCORBATE AND OXYGEN AS MODIFIERS OF THE TOXICITY AND METABOLISM OF MISONIDAZOLE INVITRO [J].

TAYLOR, YC ;

RAUTH, AM .

BRITISH JOURNAL OF CANCER, 1980, 41 (06) :892-900

← 1 2 3 →