STOCHASTIC EPIDEMICS - MAJOR OUTBREAKS AND THE DURATION OF THE ENDEMIC PERIOD

被引:81
作者
VANHERWAARDEN, OA
GRASMAN, J
机构
关键词
D O I
10.1007/BF00298644
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A study is made of a two-dimensional stochastic system that models the spread of an infectious disease in a population. An asymptotic expression is derived for the probability that a major outbreak of the disease will occur in case the number of infectives is small. For the case that a major outbreak has occurred, an asymptotic approximation is derived for the expected time that the disease is in the population. The analytical expressions are obtained by asymptotically solving Dirichlet problems based on the Fokker-Planck equation for the stochastic system. Results of numerical calculations for the analytical expressions are compared with simulation results.
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页码:581 / 601
页数:21
相关论文
共 15 条
[1]  
COURANT R, 1962, METHODS MATH PHYSICS, V2
[2]  
Edelstein-Keshet L., 1988, MATH MODELS BIOL
[3]  
Erdelyi A., 1965, ASYMPTOTIC EXPANSION
[5]  
Gardiner C. W., 1983, HDB STOCHASTIC METHO
[6]  
Goel N.S., 1974, STOCHASTIC MODELS BI
[7]   ELLIPTIC SINGULAR PERTURBATION PROBLEMS WITH TURNING POINTS [J].
KAMIN, S .
SIAM JOURNAL ON MATHEMATICAL ANALYSIS, 1979, 10 (03) :447-455
[8]  
KARLIN S, 1966, 1ST COURSE STOCHASTI
[9]  
KENDALL DG, 1956, 3RD P S MATH STAT PR, P4
[10]  
Kevorkian J., 1981, PERTURBATION METHODS