BETA-ADRENERGIC RECEPTORS ON LYMPHOBLASTS - A STUDY OF MANIC-DEPRESSIVE ILLNESS

被引：14

作者：

BERRETTINI, WH ^{[1
]}

CAPPELLARI, CB ^{[1
]}

NURNBERGER, JI ^{[1
]}

GERSHON, ES ^{[1
]}

机构：

[1] NIMH, CLIN NEUROGENET BRANCH, INTRAMURAL RES PROGRAM, BLDG 10, ROOM 3N-220, BETHESDA, MD 20892 USA

来源：

NEUROPSYCHOBIOLOGY | 1987年 / 17卷 / 1-2期

关键词：

D O I：

10.1159/000118334

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Beta-adrenergic receptor function has been the subject of much research in manic-depressive illness. Lymphoblast beta receptor binding was analyzed by Scatchard plot, using cell lines established from 17 unrelated bipolar subjects and 14 normals. No significant differences in affinity or density of beta receptors were found, in contrast to a previous report. Both the affinity and density of receptors appeared to be a stable characteristic of a cell line, as determined by repeated assay of the same cell lines.

引用

页码：15 / 18

页数：4

共 14 条

[1] PRO-OPIOMELANOCORTIN-RELATED PEPTIDES IN CEREBROSPINAL-FLUID - A STUDY OF MANIC-DEPRESSIVE DISORDER [J].