EMBRYO GROWTH-RATE IN-VITRO AS AN INDICATOR OF EMBRYO QUALITY IN IVF CYCLES

被引：24

作者：

LEWIN, A

SCHENKER, JG

SAFRAN, A

ZIGELMAN, N

AVRECH, O

ABRAMOV, Y

FRIEDLER, S

REUBINOFF, BE

机构：

[1] IVF Unit, Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical School, Ein-Kerem, Jerusalem

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 1994年 / 11卷 / 10期

关键词：

CLEAVAGE; EMBRYO; IN VITRO FERTILIZATION;

D O I：

10.1007/BF02216029

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Purpose: The role of embryo growth rate in vitro as an isolated indicator of embryo quality in IVF was evaluated retrospectively. Methods: Comparison was made between 98 cycles (group 1), in which only embryos at a cleavage stage of two to three blastomers, were transferred, and 99 cycles (group 2), in which all embryos were transferred at a cleavage stage of four or more blastomers. Embryos were transferred at a fixed interval of 42 to 44 h following oocyte insemination. The mean patients' age, number of oocytes recovered and number of embryos transferred per cycle were similar in both groups. Results: The pregnancy rate and the take-home-baby rate were significantly higher in group 2 as compared to group 1 (22.2% vs 7.1% and 16.2% vs 4.1%; P < 0.05 and P < 0.01, respectively). Conclusions: These results demonstrate that embryos with a slow cleavage rate in vitro are less likely to produce pregnancy following IVF-ET and that the cleavage stage is a valuable criteria in the selection of the best embryo for transfer.

引用

页码：500 / 503

页数：4

共 11 条

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