Molecular mechanisms of endotoxin activity

被引：15

作者：

Schletter, J

Heine, H

Ulmer, AJ

Rietschel, ET

机构：

来源：

ARCHIVES OF MICROBIOLOGY | 1995年 / 164卷 / 06期

关键词：

endotoxin; lipopolysaccharide; CD14; LPS-binding protein;

D O I：

暂无

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Endotoxin (lipopolysaccharide, LPS), a constituent of the outer membrane of the cell wall of gramnegative bacteria, exerts a wide variety of biological effects in humans. This review focuses on the molecular mechanisms underlying these activities and discusses structure-function relationships of the endotoxin molecule, its interaction with humoral and cellular receptors involved in cell activation, and transmembrane and intracellular signal transduction pathways.

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收藏

页码：383 / 389

页数：7

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