INTRAVESICAL LIGNOCAINE AND DETRUSOR INSTABILITY

被引:40
作者
HIGSON, RH [1 ]
SMITH, JC [1 ]
HILLS, W [1 ]
机构
[1] CHURCHILL HOSP,DEPT UROL,OXFORD OX3 7LJ,ENGLAND
来源
BRITISH JOURNAL OF UROLOGY | 1979年 / 51卷 / 06期
关键词
D O I
10.1111/j.1464-410X.1979.tb03587.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Summary— The effect of intravesical lignocaine solution on detrusor instability of mixed aetiology was examined in 20 patients; 40 ml of 1 % lignocaine solution with 40 ml of 8.4% sodium bicarbonate solution was instilled into the bladder. This produced increased bladder capacity in 19, altered bladder sensation in 9, changed the character of the cystometrogram in 9, and lowered the maximum detrusor pressure during bladder filling in 16. The symptomatic effect of lignocaine was short‐lived in all but one patient in whom it lasted 24 h. The possible mechanism of this inhibitory effect on bladder function is discussed. Copyright © 1979, Wiley Blackwell. All rights reserved
引用
收藏
页码:500 / 503
页数:4
相关论文
共 4 条
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  • [2] COVINO BG, 1976, LOCAL ANAESTHETICS
  • [3] GEORGE NJR, 1978, 8TH INT CONT SOC M M
  • [4] RITCHIE JM, 1965, J PHARMACOL EXP THER, V150, P152