DYNAMIC INSTABILITY OF LIQUID-LIKE MOTIONS IN A GLOBULAR PROTEIN OBSERVED BY INELASTIC NEUTRON-SCATTERING

被引：209

作者：

DOSTER, W

CUSACK, S

PETRY, W

机构：

[1] INST MAX VON LAUE PAUL LANGEVIN,EUROPEAN MOLEC BIOL LAB,GRENOBLE OUTSTN,F-38042 GRENOBLE,FRANCE

[2] INST MAX VON LAUE PAUL LANGEVIN,F-38042 GRENOBLE,FRANCE

来源：

PHYSICAL REVIEW LETTERS | 1990年 / 65卷 / 08期

关键词：

D O I：

10.1103/PhysRevLett.65.1080

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Inelastic neutron scattering was used to investigate liquidlike motions and the nature of a dynamic transition in myoglobin, a small globular protein. The signature of the transition is a strong enhancement of low-frequency density fluctuations and a corresponding decrease in elastic scattering above 180 K. It is shown that the line shape of the inelastic-scattering function approximates the scaling behavior predicted for a simple liquid by mode-coupling theories in the vicinity of the liquid-glass transition. © 1990 The American Physical Society.

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页码：1080 / 1083

页数：4

相关论文

共 32 条

[1] CO BINDING TO HEME-PROTEINS - A MODEL FOR BARRIER HEIGHT DISTRIBUTIONS AND SLOW CONFORMATIONAL-CHANGES [J].

AGMON, N ;

HOPFIELD, JJ .

JOURNAL OF CHEMICAL PHYSICS, 1983, 79 (04) :2042-2053

[2] DYNAMICS OF LIGAND-BINDING TO MYOGLOBIN [J].

AUSTIN, RH ;

BEESON, KW ;

EISENSTEIN, L ;

FRAUENFELDER, H ;

GUNSALUS, IC .

BIOCHEMISTRY, 1975, 14 (24) :5355-5373

[3] THE LIQUID GLASS-TRANSITION OF THE HARD-SPHERE SYSTEM [J].

BARRAT, JL ;

GOTZE, W ;

LATZ, A .

JOURNAL OF PHYSICS-CONDENSED MATTER, 1989, 1 (39) :7163-7170

[4] SOLVENT VISCOSITY AND PROTEIN DYNAMICS [J].

BEECE, D ;

EISENSTEIN, L ;

FRAUENFELDER, H ;

GOOD, D ;

MARDEN, MC ;

REINISCH, L ;

REYNOLDS, AH ;

SORENSEN, LB ;

YUE, KT .

BIOCHEMISTRY, 1980, 19 (23) :5147-5157

[5] DYNAMICS OF SUPERCOOLED LIQUIDS AND THE GLASS-TRANSITION [J].

BENGTZELIUS, U ;

GOTZE, W ;

SJOLANDER, A .

JOURNAL OF PHYSICS C-SOLID STATE PHYSICS, 1984, 17 (33) :5915-5934

[6] DO VIBRATIONAL SPECTROSCOPIES UNIQUELY DESCRIBE PROTEIN DYNAMICS - THE CASE FOR MYOGLOBIN [J].

BIALEK, W ;

GOLDSTEIN, RF .

BIOPHYSICAL JOURNAL, 1985, 48 (06) :1027-1044

[7] DYNAMICS OF LIGAND-BINDING TO HEME-PROTEINS [J].

CASE, DA ;

KARPLUS, M .

JOURNAL OF MOLECULAR BIOLOGY, 1979, 132 (03) :343-368

[8]

CUSACK S, IN PRESS BIOPHYS J

[9] THERMAL-PROPERTIES OF WATER IN MYOGLOBIN CRYSTALS AND SOLUTIONS AT SUBZERO TEMPERATURES [J].

DOSTER, W ;

BACHLEITNER, A ;

DUNAU, R ;

HIEBL, M ;

LUSCHER, E .

BIOPHYSICAL JOURNAL, 1986, 50 (02) :213-219

[10] DYNAMICAL TRANSITION OF MYOGLOBIN REVEALED BY INELASTIC NEUTRON-SCATTERING [J].

DOSTER, W ;

CUSACK, S ;

PETRY, W .

NATURE, 1989, 337 (6209) :754-756

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