INFLUENCE OF PLASMA CALCIUM AND VITAMIN-D ON BONE-COLLAGEN - EFFECTS ON LYSINE HYDROXYLATION AND CROSSLINK FORMATION

被引：23

作者：

DICKSON, IR

EYRE, DR

KODICEK, E

机构：

[1] CHILDRENS HOSP MED CTR,ORTHOPAED RES LABS,BOSTON,MA 02115

[2] HARVARD UNIV,SCH MED,BOSTON,MA 02115

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 588卷 / 01期

基金：

美国国家卫生研究院; 英国医学研究理事会;

关键词：

(Chicken bone); Ca[!sup]2+[!/sup; Collagen crosslinks; Lysine hydroxylation; Vitamin D;

D O I：

10.1016/0304-4165(79)90381-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In chick bone collagen the degree of lysine hydroxylation and the magnitude of the crosslink ratio dihydroxylysinonorleucine/hydroxylysinonorluecine were both found to be inversely related to the concentration of plasma calcium. Lysin hydroxylation was also affected by a second factor related to vitamine D status. © 1979.

引用

页码：169 / 173

页数：5

共 12 条

[1] BIOLOGICAL SIGNIFICANCE OF INTERMOLECULAR CROSSLINKS OF COLLAGEN
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[J]. NATURE, 1974, 251 (5471) : 105 - 109
[2] INFLUENCE OF DIETARY CALCIUM DEFICIENCY AND PARATHYROIDECTOMY ON BONE COLLAGEN STRUCTURE
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[5] AUTOMATED METHOD FOR CONTINUOUS-FLOW ANALYSIS OF RADIOACTIVITY APPLICABLE TO STUDY OF COLLAGEN CROSSLINKS
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[6] UNIQUE BIOSYNTHESIS BY KIDNEY OF A BIOLOGICALLY ACTIVE VITAMIN-D METABOLITE
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[7] EFFECT OF VITAMIN-D ON STRUCTURAL CROSSLINKS AND MATURATION OF CHICK BONE COLLAGEN
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[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 393 (02) : 419 - 425
[8] QUANTITATIVE CHANGES OF BONE COLLAGEN CROSSLINKS AND PRECURSORS IN VITAMIN-D DEFICIENCY
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[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1972, 47 (04) : 760 - &
[9] NATURE OF COLLAGEN CROSSLINKS IN BONE IN CHRONIC UREMIC STATE
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[J]. BIOCHEMICAL JOURNAL, 1975, 145 (01) : 119 - 120
[10] LYSYL HYDROXYLASE - FURTHER PURIFICATION AND CHARACTERIZATION OF ENZYME FROM CHICK-EMBRYOS AND CHICK-EMBRYO CARTILAGE
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